COVID-19 Occupational Risks, Seroprevalence and Immunity among Paramedics in Canada (CORSIP)

Status: in progress


The goal of this study is to investigate COVID-19 risk factors, infection, vaccination and immunity among paramedics in Ontario and British Columbia.


COVID-19 is a global health crisis, but the risks to specific occupational groups such as first responders have not been fully studied.  Paramedics are a very high-risk group due to the nature of their work, including treating people who are potentially infected with COVID-19. They often provide care in close proximity and transport patients in confined spaces.  Paramedics also routinely provide emergency medical treatments that may increase the risk of transmission, such as CPR for cardiac arrest.


The study aims to recruit 5,000 paramedics in Ontario and British Columbia, who will complete surveys and give blood samples three times over a one-year period.

Blood samples will be tested for antibodies to determine the proportion of paramedics who were previously infected with COVID-19 as well as the proportion who have been vaccinated. Antibodies are part of the body’s method of fighting infection, and provide a level of immunity to reinfection. For COVID-19, it is unknown how long the virus’s antibodies remain in the blood, either from previous infection or from vaccination. By measuring antibodies in the blood over time, this study will provide information on how long antibodies are produced by the body, and how this may differ between people who had a previous infection compared to those who were vaccinated.

The study will also investigate workplace factors that may impact infection, such the risk of administering certain treatments (for example, those that generate aerosols) and the benefit of infection control strategies used by their workplaces. The results will help identify factors that increase or decrease the risk of infection among paramedics, and how their risk compares to other groups such as health care workers and the general population.


This study will help identify the tasks and procedures that put paramedics most at risk of COVID-19, as well as the protective measures that can reduce their likelihood of infection. This evidence can be used to inform workplace health and safety guidelines to protect paramedics from COVID-19 and future infectious disease outbreaks, as well as seasonal flu.

Progress (updated January 2021):

The study is actively recruiting paramedics in Ontario and British Columbia. To learn more, visit


Preliminary results were presented on October 26, 2021 by Christopher MacDonald, University of Toronto.


This project is supported by funding from the Government of Canada, through the COVID-19 Immunity Task Force.

Ontario Research Team:

Dr. Tracy Kirkham (OCRC) (Principal Investigator)
Dr. Paul Demers (OCRC) (Principal Investigator)
Christopher MacDonald (University of Toronto)
Dr. Sheldon Cheskes (University of Toronto)
Dr. Ian Drennan (Sunnybrook Research Institute)

BC Research Team:

Dr. Brian Grunau (UBC) (Principal Investigator)
Dr. David Goldfarb (UBC) (Principal Investigator)
Dr. Vilte Barakauskas (UBC)
Dr. Jim Christenson (UBC)
Dr. Jocelyn Srigley (BC Provincial Health Services Authority)
Dr. Agatha Jassem (BC Centre for Disease Control)
Dr. Sandra Jenneson (BC Emergency Health Services)
Dr. Pascal Lavoie (UBC)
Dr. Julie Bettinger (UBC)
Jennie Helmer (BC Emergency Health Services)
Richard Armour (BC Emergency Health Services)
Brian Twaites (BC Emergency Health Services)
Rob Shlamp (BC Emergency Health Services)